Formula composition and nutritional quality evaluation of three pediatric balanced compound amino acid injection

balance compound amino acid injection for children; first limiting amino acid; essential amino acid; score of amino acid ratio; standard protein closeness; nutritional quality

Abstract

Through the evaluation of three kinds of pediatric balanced compound amino acid injection formula composition and nutritional quality, to provide a reference for rational drug selection in clinical practice. Methods: Based on the amino acid scoring standard model and whole egg protein model that recommended by FAO/WHO in 1973, the prescription ratio, the first restricted amino acid, the essential amino acid index, the score of ratio coefficient of amino acid, and the closeness with the standard protein of 3 kinds of pediatric balanced compound amino acid injection were evaluated.

Results: The percentage of essential amino acids in three kinds of pediatric compound amino acid injections exceeds 40% of the total amino acids, and the ratio of total EAA to AA nitrogen content was higher than 2.5. The formulations are all qualified. The first restriction amino 19AA-I was the highest, and the values order from high to low was 19AA-I>18AA-I>18AA-II. The essential amino acid index and the closeness to the standard protein were in the order of 19AA-I>18AA-I>18AA-II, and the ratio coefficient of amino acids was in the order of 18AA-I>19AA-I>18AA-II. Conclusion: 19AA-I and 18AA-I have higher nutritional quality, followed 18AA-II.